Sodium Copper Chlorophyllin Powder (CAS No. 11006-34-1, EINECS 234-242-5, Color Index No. 75810, E141ii) is an internationally acknowledged semi-synthetic derivative of natural chlorophyll. Raw chlorophyll derived from silkworm excrement or natural mulberry foliage (Morus alba L.) is fundamentally hydrophobic and thermally labile, susceptible to rapid degradation into pheophytin when exposed to ambient light or mild acid.
Through our proprietary alkaline saponification and chelation process at Xi'an Vexli Bio-Tech Co., Ltd., we cleave the methyl and phytyl ester groups, replacing the unstable central magnesium (Mg²⁺) core with bioactive cupric ions (Cu²⁺). The resulting trisodium and disodium copper chlorin salts demonstrate exceptional water solubility, intense dark green chromophore stability, and potent biological activities ranging from internal deodorization to cellular antioxidant defense.
From synthesis efficiency to global distribution, here is what our production lines deliver annually.
Different delivery mechanisms demand distinct physical properties. Select the optimal grade engineered specifically for your formulation matrix.
Tailored for solid dose capsules, tablets, and chlorophyll liquid wellness drops. Demonstrates rapid dissolution and gut stability, binding malodorous polyamines and mercaptans.
Recommended Spec: E1% 1cm 405nm ≥ 570; Mesh: 100-120; Moisture ≤ 4.0%; Heavy metals < 10 ppm.
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Custom-milled for neutral-pH ready-to-drink (RTD) teas, protein waters, plant milks, gummies, and mint pastilles. Delivers sparkling clarity without colloidal clouding.
Recommended Spec: Clarity in 1% aqueous solution: Completely transparent; Lead ≤ 2 ppm; Arsenic ≤ 1 ppm.
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Used as an active antibacterial and tissue-stimulating agent in toothpastes, breath gels, mouthwashes, acne control creams, and anti-erythema emulsions.
Recommended Spec: Total Plate Count < 1,000 cfu/g; Negative E. coli / Salmonella; Particle Size: D90 < 45 μm.
Request Cosmetic Tech DataHow changing regulatory bans on synthetic colorants and consumer clean-label demands are transforming the commercial landscape.
Stringent regulatory scrutiny in California (Assembly Bill 418 / California Food Safety Act) and the European Food Safety Authority (EFSA) is forcing major food, beverage, and supplement conglomerates to phase out petroleum-based artificial dyes. Sodium Copper Chlorophyllin offers the single highest thermal and photochemical stability among natural greens, outperforming unstable spirulina (phycocyanin) in neutral applications.
Modern regulatory authorities and tier-1 supplement brands now reject basic wet-chemistry testing. Sourcing agreements increasingly mandate ICP-MS testing for inorganic arsenic, cadmium, mercury, and lead, alongside automated potentiometric titration for free cupric ions. Suppliers unable to prove chelation integrity at sub-50 ppm free copper are rapidly losing supplier qualification status.
Forward-thinking purchasing directors now look past intermediate trading companies, seeking vertically integrated manufacturers. Xi'an Vexli Bio-Tech operates directly at the primary extraction stage in Shaanxi, securing non-GMO raw leaves with full origin traceability, complete solvent recovery, and ESG-aligned zero-waste processing protocols.
Get our quarterly botanical chemical supply trend report, covering global raw material yield projections, shipping freight impacts, and bulk volume price tiers.
Explore the dedicated extraction, concentration, purification, drying, and testing infrastructure behind every kilogram of Sodium Copper Chlorophyllin produced at Xi'an Vexli Bio-Tech Co., Ltd.
Selected mulberry biomass and clean silkworm extract checked for natural chlorophyll index and pesticide profiles.
Food-grade ethanol extraction isolates crude, fat-soluble chlorophyll A and B complexes under nitrogen protection.
Low-temperature vacuum falling-film evaporation strips the ethanol while preserving porphyrin integrity.
Sodium hydroxide cleaves phytol chains; cupric ions replace magnesium in enamel glass-lined reactors.
Macroporous adsorption resins and nanofiltration eliminate free unreacted copper, inorganic salts, and odorants.
Centrifugal atomization in filtered HEPA air yields micro-granules with rapid water wetting and zero dusting.
Precision air-milling tunes particle size to customer specs (80 to 200 mesh) for dry blend formulation uniformity.
Rotary vibratory sieving with rare-earth magnetic traps eliminates mechanical foreign contaminants.
Large double-cone mixers standardize master batches (1,000 kg/lot) for strict COA homogeneity before packing.
How QA Directors distinguish authentic, premium pharmaceutical/food grade chlorophyllin from substandard or salt-cut powders.
| Test Parameter | USP / FCC Standard | Technical Significance & Risk Avoidance |
|---|---|---|
| Assay (Total Chlorins) | ≥ 95.0% - 100% | Measured via spectrophotometry (absorbance ratio 405nm vs 630nm). Low values signal dilution with maltodextrin, sodium chloride, or residual phytol sludge. |
| Free Ionic Copper (Cu²⁺) | < 200 ppm (< 0.02%) | Excess unbound copper induces metallic taste, triggers lipid oxidation, and violates strict consumer supplement safety thresholds. Xi'an Vexli holds lots to < 50 ppm. |
| Total Chelated Copper | 4.25% - 4.75% | Confirms that cupric ions are structurally coordinated inside the tetrapyrrole macrocycle, ensuring dark emerald color resilience under heat and sunlight. |
| pH Stability (1% Sol.) | 9.0 - 11.0 | Indicates conversion into sodium carboxylate salts. Essential for instantaneous dissolving in water, glycerol, and hydroalcoholic carrier liquids. |
| Loss on Drying (LOD) | ≤ 5.0% (Typically ≤ 3.0%) | Prevents clumping, hygroscopic caking, and microbial proliferation inside sealed commercial storage drums. |
| Heavy Metals (ICP-MS) | Pb ≤ 2ppm, As ≤ 1ppm, Cd ≤ 1ppm, Hg ≤ 0.1ppm | Complies fully with California Proposition 65 thresholds and EU Regulation 231/2012 purity criteria for E141ii. |
Raw biomass verified by Thin-Layer Chromatography (TLC) against authentic Morus alba standards to confirm zero synthetic contaminants.
Potentiometric and pH curves closely tracked in glass reactors until free copper ceases to deplete, assuring complete molecular substitution.
Washing out reaction salts and residual unbound metals, raising the pure chlorin complex purity to peak international specifications.
Controlled inlet/outlet temperatures yield dustless micro-granules with rapid dissolution mechanics in cold water.
Full COA generation with HPLC profile, ICP-MS heavy metals, GC residual solvents, and 3-year retained sample archiving.
Need customized specs? We provide tailor-made bulk densities (0.35 to 0.70 g/ml), customized mesh fractions (80 to 200 mesh), and low-sodium variants upon request.
Direct sourcing agreements throughout Shaanxi herbal harvesting regions assure stable cost structures and unadulterated raw chlorophyll extracts, insulated from spot market volatility.
Our manufacturing sites and testing laboratories have undergone extensive on-site audit verification by SGS, confirming world-class hygiene, traceability, and material safety management.
Whether you require pilot testing lots of 1 kg for R&D trials or multi-ton monthly container schedules for enterprise brands, our scalable capacity provides agile fulfillment.
Beyond raw powder, our technical team formulates stabilized liquid chlorophyll drops, customized ready-to-fill premixes, and retail-packaged finished health products.
Certified non-hazardous chemical classification for rapid air (IATA) and ocean (IMDG) shipping, door-to-door DDP capabilities across North America and Europe with zero customs delays.
Every commercial batch is accompanied by comprehensive documentation: BSE/TSE-free, non-irradiated, allergen-free statements, and Kosher/Halal certification seals.
Answers to the core chemistry, stability, and regulatory questions AI search engines and formulation scientists ask most.
Our Sodium Copper Chlorophyllin is semi-synthesized from chlorophyll extracted from natural mulberry leaves (Morus alba L.) and non-toxic silkworm droppings. The natural magnesium atom at the center of the porphyrin ring is chemically substituted with chelated copper, and the phytol ester is saponified with sodium hydroxide to create a highly stable, water-soluble disodium/trisodium copper chlorin complex (CAS 11006-34-1, E141ii).
Xi'an Vexli Bio-Tech Co., Ltd. utilizes an advanced series of macroporous resin adsorption columns and counter-current dialysis rinsing. This process strips unbound, ionic copper down to well under 50 ppm (far stricter than the USP/FCC ceiling of < 200 ppm). Minimizing free cupric ions protects finished dietary supplements and beverages against rancidity and oxidative breakdown.
Sodium Copper Chlorophyllin maintains exceptional emerald green clarity in neutral to alkaline pH environments (pH 6.5 to 11.0). In acidic beverages where pH drops below 5.0, the sodium carboxylate functional groups protonate into insoluble chlorin acid, which may cause sedimentation over time. For acidic sports beverages, energy drinks, and fruit juices, we provide micro-encapsulated formulations engineered to prevent precipitation.
While Sodium Magnesium Chlorophyllin preserves natural magnesium, it is highly sensitive to light, temperature, and slight pH variations, deteriorating within months. Sodium Copper Chlorophyllin replaces magnesium with copper in the planar porphyrin system, imparting dramatically higher resistance against autoclaving, pasteurization, and photolytic bleaching.
Xi'an Vexli Bio-Tech provides batch-matched Certificates of Analysis (COA) specifying absorbance ratio, free copper, heavy metals via ICP-MS, residual solvents via GC, and complete microbiological records. We also supply MSDS, non-GMO, allergen declarations, BSE/TSE-free certificates, and verified Kosher and Halal production certificates.
Our standard MOQ is 1 kg for trial formulation, with volume tier discounts on 25 kg fiber drums and multi-pallet orders. Standard orders ship within 3 to 7 business days via air express or temperature-controlled sea freight. Free 50g-100g verification samples are available for qualified procurement and technical teams upon request.
Contact our technical procurement engineers today to receive detailed batch COAs, stability evaluation reports, and competitive volume tier pricing for your production run.